Michail Tsodyks, PhD

Departments And Divisions

  • Department of Neuroscience
  • Assistant Professor of Neuroscience
Michail Tsodyks, <span>PhD</span>

Theoretical models of working memory and episodic memory

The classical view is that working memory is mediated by persistent firing of selective groups of neurons. Recently, Misha Tsodyks proposed that working memory could be carried by selective short-term synaptic facilitation in neocortical connections, particularly, in the prefrontal cortex. The synaptic mechanism is more robust than persistent firing but requires a control system that would extract the information from synaptic into spiking form when it must be processed. In collaboration with experimental labs studying memory in humans and monkeys, Tsodyks is studying the implications of this theory for working memory capacity and recall of information from episodic memory. 

Lab Locations

  • Kolb Research Annex

    40 Haven Avenue
    Unit 87, Room 727
    New York, NY 10032
    Phone:
    (646) 774-7339
    Email:
    mt2450@cumc.columbia.edu

Past Positions

Oct 2005 – Professor
Weizmann Institute of Science, Department of Neurobiology

Oct 2000 – Oct 2005 – Associate Professor
Weizmann Institute of Science, Department of Neurobiology

May 1995 - Oct 2000 - Senior Investigator
Weizmann Institute of Science, Department of Neurobiology

Jan 1994 - May 1995 - Howards Hughes Medical Institute Research Associate
Salk Institute of Biological Studies, San Diego

Sept 1990 - Dec1993 - Researcher
Hebrew University of Jerusalem, Racah Institute of Physics

May1987 – Sept 1990 – Researcher
The Institute of Higher Nervous Activity & Neuro-physiology,
USSR Academy of Sciences, Moscow

Long-Term Visiting Positions
2007 - Columbia University, New York
2006 - 2008 Ecole Normale Superieure, Paris
2005 - Frankfurt Institute for Advanced Studies
2003 - Ecole Poletechnique, Lusanne
2001 - UC Santa Barbara

Other Appointments
2007 - Frontiers of Computational Neuroscience, Chief Editor.
2006 - Faculty of 1000, Theoretical & Computational Neuroscience, Section Head
2000 - Journal of Computational Neuroscience', Member of the Editorial Board
1999 - 2007 Neural Networks', Member of the Editorial Board
1999 - 2003 Hippocampus', Member of the Editorial Board
1995 - Member of Israeli Society of Neuroscience
1994 - Member of American Society of Neuroscience

Honors & Awards

1994 - Howard Hughes fellowhsip, San Diego
1997 - Morris L. Levinson Biology Prize of the Weizmann Institute Scientific Council for 1997

Research Interests

  • Theoretical Neuroscience
  • Computation and Theory

Publications

O. Barak, M. Tsodyks & R. Romo. “Neuronal population coding of parametric working memory”. J. of Neurosci. 30:9424-9430 (2010).
S. Romani & M. Tsodyks. “Continuous attractors with morphed/correlated maps”. PLoS Comput. Biology. 6 (2010).
S. Romani, T. Sejnowski, M. Tsodyks. ” Intracellular Dynamics of Virtual Place Cells. Neural Computation, 23: 651-655 (2011).
V. Itskov, D. Hansel & M. Tsodyks. “Short-Term Facilitation may Stabilize Parametric Working Memory Trace. Front Comput Neurosci. 5:40 (2011).
S. Mark & M. Tsodyks. “Population spikes in cortical networks during different functional states”. Front Comput Neurosci. 6:43 (2012).
O. Barak, D. Sussillo, R. Romo, M. Tsodyks & L. Abbott. “From fixed points to chaos: three models of delayed discrimination. Prog. Neurobiol. 102:213-22 (2013).
S. Romani, I. Pinkoviezky, A. Rubin & M. Tsodyks. Scaling laws of associative memory retrieval. Neural Computation. 25:2523-2544 (2013).
C. Tetzlaff, C. Kolodziejski, M. Timme, M. Tsodyks & F. Worgotter. Synaptic scaling enables dynamically distinct short- and long-term memory formation. PloS Comput. Biol. 9:e1003307 (2013).
B. Si, S. Romani & M. Tsodyks. Continuous attractor network model for conjunctive position-by-velocity tuning of grid cells. PloS Comput. Biol. 10: e1003558 (2014).
S. Romani & M. Tsodyks. Short-term plasticity based network model of place cell dynamics. Hippocampus, 25:94-105 (2015).
M. Katkov, S. Romani & M. Tsodyks. World length effect in randomly assembled word lists. Front. Comput. Neurosci. doi: 10.3389/fncom.2014.00129 (2014).
M. Katkov, S. Romani & M. Tsodyks. Effects of long-term representations in free recall of unrelated words. Learning and memory, 22:101-108 (2015).

For a complete list of publications, please visit PubMed.gov